After the Virginia Tech and Pittsburgh football teams have begun the season perfectly at 4-0, the two will face off on Friday night at Lane Stadium in Blacksburg in a massive primetime showdown that will have a lot of eyes on it. When the ball is kicked off, the two teams will make history as the only two undefeated Power 4 teams to meet this late in the season without either team being ranked.
Virginia Tech head coach James Franklin and Pitt coach Pat Narduzzi don't care about that and are just focusing on winning the game. Whoever wins the game should be ranked in Sunday's Associated Press Top 25 poll. Let's take a look at the latest odds and make a prediction for the biggest game in almost a decade in Blacksburg.
Virginia Tech vs. Boston College: Final odds, spread, and total
Odds provided by DraftKings Sportsbook
Moneyline
- Virginia Tech (-162)
- Pittsburgh (+136)
Spread
- Virginia Tech -3 (-115)
- Pittsburgh +3 (-105)
Total
- 54.5 (over -118/under -102)
Virginia Tech vs. Pittsburgh Prediction
This is an interesting matchup. This is Pittsburgh's first true road game of the season, as the first four games they have played have been at home against Miami of Ohio, Central Florida, Syracuse, and Bucknell. The Hokies have won home games against VMI and Old Dominion, as well as road games the last two weeks at Maryland and Boston College. The latter was played in a Nor'easter and required a fourth-quarter rally to remain undefeated.
This is a matchup between two teams that have proven to have explosive offenses with young and talented quarterbacks. The question is going to come down to the defenses. Which unit will create more turnovers? Will Pitt's defensive line be a problem for Virginia Tech's patchwork offensive line? Will the Hokies' crowd affect the Panthers' offense, which is on the road for the first time in 2026? So many questions will be answered that will have an effect on the outcome.
In the end, this is a complete toss-up, but the Hokies secondary has been struggling this season, and with Panthers QB Mason Heintschel, if he gets into a rhythm, it could be a long night for Brent Pry's crew. Going with the gut, not the heart.
